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Job Title | Post-Doctoral Scholar |
---|---|
Requisition Number | DU10421 |
Department Name | 8E030:Chemistry |
Work Location | Lexington, KY |
Salary Range | 47,476.00 |
Type of Position | Temporary |
Position Time Status | Full-Time |
Required Education | Ph.D. in chemistry or a related field |
Required Related Experience | have a PhD in chemistry or a related field, with experience expressing and purifying proteins from cloned genes, basic spectroscopy and titrations. |
Required License/Registration/Certification | n/a |
Physical Requirements | Capacity for occasional long days, for when experiments cannot be paused |
Shift | N/A |
Job Summary | A postdoctoral position is available with Prof. A.-F. Miller at the University of Kentucky. Research projects involve production, mutation, immobilization and characterization of flavin-containing enzymes critical to energy metabolism and, electron transfer. The project goals are to articulate principles underlying the extraordinary efficiency, speed and activity of biological enzymes so that the principles can be implemented in novel materials and devices. The specific targets are flavoenzymes that execute electron transfer bifurcation, to learn how they are able to produce higher-energy reductants based on less reactive (but more abundant) fuel. Activities will include computational, spectroscopic, kinetic and thermodynamic characterizations to elucidate protein-flavin interactions underlying activity. A description of our research activities and a list of recent publications can be found at https://scholar.google.com/scholar?as_ylo=2022&q=%22anne-frances+miller%22++university+of+kentucky&hl=en&as_sdt=0,18. The position is initially for one year at an annual rate of $47,476 (US) plus benefits and can be extended upon mutual agreement. The University of Kentucky is located in Lexington-the heart of the Kentucky’s beautiful bluegrass region. Applicants should have a PhD in chemistry or a related field, with experience expressing and purifying proteins from cloned genes, basic spectroscopy and titrations. Additional valuable skills include at least some of QM/MM computation, kinetic enzyme assays, electrochemistry. Review of applications will begin immediately and continue until the position is filled. |
Skills / Knowledge / Abilities | see job summary above |
Does this position have supervisory responsibilities? | No |
Preferred Education/Experience | Required: PhD in chemistry or biochemistry or chemical engineering. Required: experience expressing and purifying proteins from cloned genes, bacterial cultures, preparation of solutions, basic spectrophotometry (UV,visible), titrations, data analysis, production of figures, maintenance of good records, compliance with all safety, accountability, archiving requirements, team player in lab including hygiene of shared spaces, resources and instruments. Experience with half of the following is also required (the other half can be learned): reduction midpoint potential determination by spectroelectrochemistry, direct electrochemistry, kinetic enzyme assays, NMR spectroscopy, EPR spectroscopy, MD computation, QMMM computation, anaereobic technique, numerical deconvolution of series of spectra (can be via python coding), oversight and guidance of junior colleagues, production of manuscript drafts, maintainance of shared instrumentation and provision of training, preparation of graphics and delivery of presentations on own work. |
Deadline to Apply | 06/30/2023 |
University Community of Inclusion | The University of Kentucky is committed to a diverse and inclusive workforce by ensuring all our students, faculty, and staff work in an environment of openness and acceptance. We strive to foster a community where people of all backgrounds, identities, and perspectives can feel secure and welcome. We also value the well-being of each of our employees and are dedicated to creating a healthy place to work, learn and live. In the interest of maintaining a safe and healthy environment for our students, employees, patients and visitors the University of Kentucky is a Tobacco & Drug Free campus. |
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